A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme

The blossom of immunotherapy in melanoma highlights the need to delineate mechanisms of immune resistance. Recently, we have demonstrated that the RNA editing protein, adenosine deaminase acting on RNA-1 (ADAR1) is down-regulated during metastatic transition of melanoma, which enhances melanoma cell...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Galore-Haskel, Gilli, Nemlich, Yael, Greenberg, Eyal, Ashkenazi, Shira, Hakim, Motti, Itzhaki, Orit, Shoshani, Noa, Shapira-Fromer, Ronnie, Ben-Ami, Eytan, Ofek, Efrat, Anafi, Liat, Besser, Michal J., Schachter, Jacob, Markel, Gal
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745707/
https://ncbi.nlm.nih.gov/pubmed/26338962
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