Inhibition of 13-cis retinoic acid-induced gene expression of reactive-resistance genes by thalidomide in glioblastoma tumours in vivo

The cell differentiation potential of 13-cis retinoic acid (RA) has not succeeded in the clinical treatment of glioblastoma (GBM) so far. However, RA may also induce the expression of resistance genes such as HOXB7 which can be suppressed by Thalidomide (THAL). Therefore, we tested if combined treat...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Milanovic, Dusan, Sticht, Carsten, Röhrich, Manuel, Maier, Patrick, Grosu, Anca-L., Herskind, Carsten
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745702/
https://ncbi.nlm.nih.gov/pubmed/26362268
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