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GREM1 germline mutation screening in Ashkenazi Jewish patients with familial colorectal cancer
Background: A 40 kb ancestral germline duplication upstream of the GREM1 gene was reported in Ashkenazi families with hereditary mixed polyposis syndrome (HMPS). Objective: Assess the contribution of the GREM1 mutation to familial colorectal cancer (CRC) in Ashkenazim. Methods: Jewish Ashkenazi indi...
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| Publicat a: | Genet Res (Camb) |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cambridge University Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4745135/ https://ncbi.nlm.nih.gov/pubmed/25992589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0016672315000105 |
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