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Substrate bound outward-open state of BetP: insights into Na(+) coupling

The Na(+)-coupled betaine symporter BetP shares a highly conserved fold with other sequence unrelated secondary transporters, e.g., with neurotransmitter symporters. Recently, we obtained atomic structures of BetP in distinct conformational states, which elucidated parts of its alternating access me...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Perez, Camilo, Faust, Belinda, Mehdipour, Ahmad Reza, Francesconi, Kevin A., Forrest, Lucy R., Ziegler, Christine
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745115/
https://ncbi.nlm.nih.gov/pubmed/25023443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5231
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