The Synthesis of Quinolone Natural Products from Pseudonocardia sp.

The synthesis of four quinolone natural products from the actinomycete Pseudonocardia sp. is reported. The key step involved a sp(2)–sp(3) Suzuki–Miyaura reaction between a common boronic ester lateral chain and various functionalised quinolone cores. The quinolones slowed growth of E. coli and S. a...

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Udgivet i:European J Org Chem
Main Authors: Salvaggio, Flavia, Hodgkinson, James T., Carro, Laura, Geddis, Stephen M., Galloway, Warren R. J. D., Welch, Martin, Spring, David R.
Format: Artigo
Sprog:Inglês
Udgivet: WILEY‐VCH Verlag 2015
Fag:
Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744947/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201501400
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