Microenvironmental control of stem cell fate in intestinal homeostasis and disease

The conventional model of intestinal epithelial architecture describes a unidirectional tissue organizational hierarchy with stem cells situated at the crypt base and daughter cells proliferating and terminally differentiating as they progress along the vertical (crypt–luminal) axis. In this model,...

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Bibliographic Details
Published in:J Pathol
Main Authors: Biswas, Sujata, Davis, Hayley, Irshad, Shazia, Sandberg, Tessa, Worthley, Daniel, Leedham, Simon
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Invited Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744721/
https://ncbi.nlm.nih.gov/pubmed/25974319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4563
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