Tracking of the origin of recurrent mutations of the BRCA1 and BRCA2 genes in the North-East of Italy and improved mutation analysis strategy

BACKGROUND: About 20 % of hereditary breast cancers are caused by mutations in BRCA1 and BRCA2 genes. Since BRCA1 and BRCA2 mutations may be spread throughout the gene, genetic testing is usually performed by direct sequencing of entire coding regions. In some populations, especially if relatively i...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:BMC Med Genet
Glavni autori: Cini, Giulia, Mezzavilla, Massimo, Della Puppa, Lara, Cupelli, Elisa, Fornasin, Alessio, D’Elia, Angela Valentina, Dolcetti, Riccardo, Damante, Giuseppe, Bertok, Sara, Miolo, Gianmaria, Maestro, Roberta, de Paoli, Paolo, Amoroso, Antonio, Viel, Alessandra
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744627/
https://ncbi.nlm.nih.gov/pubmed/26852130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-016-0274-6
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items