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Sustained Pulmonary Delivery of a Water-Soluble Antibiotic Without Encapsulating Carriers

PURPOSE: Traditional polymeric nanoparticle formulations for prolonged local action during inhalation therapy are highly susceptible to muco-ciliary clearance. In addition, polymeric carriers are typically administered in high doses due to finite drug loading. For toxicological reasons, these carrie...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Ong, Winston, Nowak, Pawel, Cu, Yen, Schopf, Lisa, Bourass, James, Enlow, Elizabeth, Moskowitz, Samuel M., Chen, Hongming
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744570/
https://ncbi.nlm.nih.gov/pubmed/26508478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1808-x
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