Molecular analysis of lipid reactive Vδ1 γδ T cells identified by CD1c tetramers

CD1c is abundantly expressed on human dendritic cells (DC) and B cells, where it binds and displays lipid antigens to T cells. Here we report that CD1c tetramers carrying M. tuberculosis phosphomycoketide bind γδ T cell receptors (TCRs). An unbiased method of ligand-based TCR selection detects inter...

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Publicado en:J Immunol
Main Authors: Roy, Sobhan, Ly, Dalam, Castro, Caitlin D., Li, Nan-Sheng, Hawk, Andrew J., Altman, John D., Meredith, Stephen C., Piccirilli, Joseph A., Moody, D. Branch, Adams, Erin J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744554/
https://ncbi.nlm.nih.gov/pubmed/26755823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502202
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