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miR-223 Regulates mDC-Driven T(H)17 Responses in Experimental Autoimmune Encephalomyelitis

Myeloid cells play a crucial role in the induction and sustained inflammation in neuroinflammatory disorders such as MS. miR-223, a myeloid cell-specific miRNA, is one of the most upregulated miRNAs in MS patients. We demonstrate that miR-223 KO mice display significantly reduced active and adoptive...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Ifergan, Igal, Chen, Siqi, Zhang, Bin, Miller, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744529/
https://ncbi.nlm.nih.gov/pubmed/26783338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501965
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