Ca(2+) Effects on ATP Production and Consumption Have Regulatory Roles on Oscillatory Islet Activity

Pancreatic islets respond to elevated blood glucose by secreting pulses of insulin that parallel oscillations in β-cell metabolism, intracellular Ca(2+) concentration, and bursting electrical activity. The mechanisms that maintain an oscillatory response are not fully understood, yet several models...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: McKenna, Joseph P., Ha, Joon, Merrins, Matthew J., Satin, Leslie S., Sherman, Arthur, Bertram, Richard
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2016
Fag:
Systems Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744176/
https://ncbi.nlm.nih.gov/pubmed/26840737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.11.3526
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