The Position of His-Tag in Recombinant OspC and Application of Various Adjuvants Affects the Intensity and Quality of Specific Antibody Response after Immunization of Experimental Mice

Lyme disease, Borrelia burgdorferi-caused infection, if not recognized and appropriately treated by antibiotics, may lead to chronic complications, thus stressing the need for protective vaccine development. The immune protection is mediated by phagocytic cells and by Borrelia-specific complement-ac...

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Publicado en:PLoS One
Main Authors: Krupka, Michal, Masek, Josef, Barkocziova, Lucia, Turanek Knotigova, Pavlina, Kulich, Pavel, Plockova, Jana, Lukac, Robert, Bartheldyova, Eliska, Koudelka, Stepan, Chaloupkova, Radka, Sebela, Marek, Zyka, Daniel, Droz, Ladislav, Effenberg, Roman, Ledvina, Miroslav, Miller, Andrew D., Turanek, Jaroslav, Raska, Milan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744052/
https://ncbi.nlm.nih.gov/pubmed/26848589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148497
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