Congenic Strains Confirm the Pleiotropic Effect of Chromosome 4 QTL on Mouse Femoral Geometry and Biomechanical Performance

A pleiotropic quantitative trait locus (QTL) for bone geometry and mechanical performance in mice was mapped to distal chromosome 4 via an intercross of recombinant congenic mice HcB-8 and HcB-23. To study the QTL in isolation, we have generated C3H.B10-(rs6355453-rs13478087) (C.B.4.3) and C3H.B10-(...

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Pubblicato in:PLoS One
Autori principali: Kristianto, Jasmin, Litscher, Suzanne J., Johnson, Michael G., Patel, Forum, Patel, Mital, Fisher, Jacqueline, Zastrow, Ryley K., Radcliff, Abigail B., Blank, Robert D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743951/
https://ncbi.nlm.nih.gov/pubmed/26849124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148571
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