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Targeting an Essential GTPase Obg for the Development of Broad-Spectrum Antibiotics

A promising new drug target for the development of novel broad-spectrum antibiotics is the highly conserved small GTPase Obg (YhbZ, CgtA), a protein essential for the survival of all bacteria including Neisseria gonorrhoeae (GC). GC is the agent of gonorrhea, a prevalent sexually transmitted disease...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Bonventre, Josephine A., Zielke, Ryszard A., Korotkov, Konstantin V., Sikora, Aleksandra E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743925/
https://ncbi.nlm.nih.gov/pubmed/26848972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148222
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