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Emerging proteomic technologies for elucidating context-dependent cellular signaling events: A big challenge of tiny proportions

Aberrant cell signaling events either drive or compensate for nearly all pathologies. A thorough description and quantification of maladaptive signaling flux in disease is a critical step in drug development, and complex proteomic approaches can provide valuable mechanistic insights. Traditional pro...

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Bibliographic Details
Published in:Proteomics
Main Authors: Parker, Sarah J, Raedschelders, Koen, Van Eyk, Jennifer E
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743877/
https://ncbi.nlm.nih.gov/pubmed/25545106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400448
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