Distance from sub-Saharan Africa predicts mutational load in diverse human genomes

The Out-of-Africa (OOA) dispersal ∼50,000 y ago is characterized by a series of founder events as modern humans expanded into multiple continents. Population genetics theory predicts an increase of mutational load in populations undergoing serial founder effects during range expansions. To test this...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Henn, Brenna M., Botigué, Laura R., Peischl, Stephan, Dupanloup, Isabelle, Lipatov, Mikhail, Maples, Brian K., Martin, Alicia R., Musharoff, Shaila, Cann, Howard, Snyder, Michael P., Excoffier, Laurent, Kidd, Jeffrey M., Bustamante, Carlos D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743782/
https://ncbi.nlm.nih.gov/pubmed/26712023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510805112
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