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Evaluation of CTX-M steady-state mRNA, mRNA half-life and protein production in various STs of Escherichia coli

OBJECTIVES: High levels of β-lactamase production can impact treatment with a β-lactam/β-lactamase inhibitor combination. Goals of this study were to: (i) compare the mRNA and protein levels of CTX-M-15- and CTX-M-14-producing Escherichia coli from 18 different STs and 10 different phylotypes; (ii)...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Geyer, Chelsie N., Fowler, Randal C., Johnson, James R., Johnston, Brian, Weissman, Scott J., Hawkey, Peter, Hanson, Nancy D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743699/
https://ncbi.nlm.nih.gov/pubmed/26612874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv388
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