Deep sequencing of HIV-1 variants from paired plasma and cerebrospinal fluid during primary HIV infection

BACKGROUND: : Limited data exist comparing viral quasispecies between cerebrospinal fluid (CSF) and plasma compartments during primary HIV infection. Deep sequencing is a new method to examine the HIV plasma and CSF quasispecies. METHODS: : In this pilot study, deep sequencing of protease (PR) and r...

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Dettagli Bibliografici
Pubblicato in:J Virus Erad
Autori principali: Gega, Arjet, Kozal, Michael J, Chiarella, Jennifer, Lee, Evelyn, Peterson, Julia, Hecht, Frederick M, Liegler, Teri, St John, Elizabeth P, Simen, Birgitte B, Price, Richard W, Spudich, Serena S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mediscript Ltd 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743659/
https://ncbi.nlm.nih.gov/pubmed/26855971
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