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Classification of P-glycoprotein-interacting compounds using machine learning methods
P-glycoprotein (Pgp) is a drug transporter that plays important roles in multidrug resistance and drug pharmacokinetics. The inhibition of Pgp has become a notable strategy for combating multidrug-resistant cancers and improving therapeutic outcomes. However, the polyspecific nature of Pgp, together...
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| Опубликовано в: : | EXCLI J |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Leibniz Research Centre for Working Environment and Human Factors
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743480/ https://ncbi.nlm.nih.gov/pubmed/26862321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2015-374 |
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