Feasibility outcomes of a presurgical randomized controlled trial exploring the impact of caloric restriction and increased physical activity versus a wait-list control on tumor characteristics and circulating biomarkers in men electing prostatectomy for prostate cancer

BACKGROUND: Obesity is associated with tumor aggressiveness and disease-specific mortality for more than 15 defined malignancies, including prostate cancer. Preclinical studies suggest that weight loss from caloric restriction and increased physical activity may suppress hormonal, energy-sensing, an...

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Pubblicato in:BMC Cancer
Autori principali: Demark-Wahnefried, Wendy, Nix, Jeffery W., Hunter, Gary R., Rais-Bahrami, Soroush, Desmond, Renee A., Chacko, Balu, Morrow, Casey D., Azrad, Maria, Frugé, Andrew D., Tsuruta, Yuko, Ptacek, Travis, Tully, Scott A., Segal, Roanne, Grizzle, William E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743419/
https://ncbi.nlm.nih.gov/pubmed/26850040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2075-x
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