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Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

Little is known about how cells ensure DNA replication in the face of RNA polymerase II (RNAPII)-mediated transcription, especially under conditions of replicative stress. Here we present genetic and proteomic analyses from budding yeast that uncover links between the DNA replication checkpoint sens...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Poli, Jérôme, Gerhold, Christian-Benedikt, Tosi, Alessandro, Hustedt, Nicole, Seeber, Andrew, Sack, Ragna, Herzog, Franz, Pasero, Philippe, Shimada, Kenji, Hopfner, Karl-Peter, Gasser, Susan M.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743062/
https://ncbi.nlm.nih.gov/pubmed/26798134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.273813.115
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