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Structural basis for human PRDM9 action at recombination hot spots
The multidomain zinc finger (ZnF) protein PRDM9 (PRD1–BF1–RIZ1 homologous domain-containing 9) is thought to influence the locations of recombination hot spots during meiosis by sequence-specific DNA binding and trimethylation of histone H3 Lys4. The most common variant of human PRDM9, allele A (hPR...
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| I publikationen: | Genes Dev |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743056/ https://ncbi.nlm.nih.gov/pubmed/26833727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.274928.115 |
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