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Transplanted neurons integrate into adult retinas and respond to light

Retinal ganglion cells (RGCs) degenerate in diseases like glaucoma and are not replaced in adult mammals. Here we investigate whether transplanted RGCs can integrate into the mature retina. We have transplanted GFP-labelled RGCs into uninjured rat retinas in vivo by intravitreal injection. Transplan...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Venugopalan, Praseeda, Wang, Yan, Nguyen, Tu, Huang, Abigail, Muller, Kenneth J., Goldberg, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742891/
https://ncbi.nlm.nih.gov/pubmed/26843334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10472
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