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Diapause is associated with a change in the polarity of secretion of insulin-like peptides

The insulin/IGF-1 signalling (IIS) pathway plays an important role in the regulation of larval diapause, the long-lived growth arrest state called dauer arrest, in Caenorhabditis elegans. In this nematode, 40 insulin-like peptides (ILPs) have been identified as putative ligands of the IIS pathway; h...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Matsunaga, Yohei, Honda, Yoko, Honda, Shuji, Iwasaki, Takashi, Qadota, Hiroshi, Benian, Guy M., Kawano, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742890/
https://ncbi.nlm.nih.gov/pubmed/26838180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10573
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