Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment

Rapidly growing tumours in vivo often outgrow their surrounding available blood supply, subjecting themselves to a severely hypoxic microenvironment. Understanding how tumour cells adapt themselves to survive hypoxia may help to develop new treatments of the tumours. Given the limited blood perfusio...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Dong, Hangming, Zou, Mengchen, Bhatia, Ayesha, Jayaprakash, Priyamvada, Hofman, Florence, Ying, Qilong, Chen, Mei, Woodley, David T., Li, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742873/
https://ncbi.nlm.nih.gov/pubmed/26846992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20605
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