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Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages

Sustained epidermal Wnt/β-catenin signalling expands the stem cell compartment and induces ectopic hair follicles (EFs). This is accompanied by extensive fibroblast proliferation and extracellular matrix (ECM) remodelling in the underlying dermis. Here we show that epidermal Hedgehog (Hh) and Transf...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Lichtenberger, Beate M., Mastrogiannaki, Maria, Watt, Fiona M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742837/
https://ncbi.nlm.nih.gov/pubmed/26837596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10537
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