The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I

Although ribosomal RNA represents the majority of cellular RNA, and ribosome synthesis is closely connected to cell growth and proliferation rates, a complete understanding of the factors that influence transcription of ribosomal DNA is lacking. Here, we show that the THO complex positively affects...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhang, Yinfeng, French, Sarah L., Beyer, Ann L., Schneider, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742762/
https://ncbi.nlm.nih.gov/pubmed/26663077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.673442
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