A carregar...
HIV-1 Vpr Protein Induces Proteasomal Degradation of Chromatin-associated Class I HDACs to Overcome Latent Infection of Macrophages
Mechanisms underlying HIV-1 latency remain among the most crucial questions that need to be answered to adopt strategies for purging the latent viral reservoirs. Here we show that HIV-1 accessory protein Vpr induces depletion of class I HDACs, including HDAC1, 2, 3, and 8, to overcome latency in mac...
Na minha lista:
| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742738/ https://ncbi.nlm.nih.gov/pubmed/26679995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.689018 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|