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GPER1-mediated IGFBP-1 induction modulates IGF-1-dependent signaling in tamoxifen-treated breast cancer cells

Tamoxifen, a selective estrogen receptor modulator, is a commonly prescribed adjuvant therapy for estrogen receptor-α (ERα)-positive breast cancer patients. To determine if extracellular factors contribute to the modulation of IGF-1 signaling after tamoxifen treatment, MCF-7 cells were treated with...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Vaziri-Gohar, Ali, Houston, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742395/
https://ncbi.nlm.nih.gov/pubmed/26690777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.11.033
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