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Biogenesis and regulation of the let-7 miRNAs and their functional implications

The let-7 miRNA was one of the first miRNAs discovered in the nematode, Caenorhabditis elegans, and its biological functions show a high level of evolutionary conservation from the nematode to the human. Unlike in C. elegans, higher animals have multiple isoforms of let-7 miRNAs; these isoforms shar...

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Podrobná bibliografie
Vydáno v:Protein Cell
Hlavní autoři: Lee, Hosuk, Han, Sungwook, Kwon, Chang Seob, Lee, Daeyoup
Médium: Artigo
Jazyk:Inglês
Vydáno: Higher Education Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742387/
https://ncbi.nlm.nih.gov/pubmed/26399619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0212-y
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