Mechanisms of dihydrotestosterone action on resveratrol-induced anti-proliferation in breast cancer cells with different ERα status

Dihydrotestosterone (DHT) has been shown to promote breast cancer growth via different mechanisms. In addition to binding to ERα, the DHT membrane receptor exists on integrin αvβ3. Resveratrol induces p53-dependent apoptosis via plasma membrane integrin αvβ3. Resveratrol and DHT signals are both tra...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Chin, Yu-Tang, Yang, Sheng-Huei, Chang, Tung-Cheng, Changou, Chun A., Lai, Hsuan-Yu, Fu, Earl, HuangFu, Wei-Chun, Davis, Paul J., Lin, Hung-Yun, Liu, Leroy F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742147/
https://ncbi.nlm.nih.gov/pubmed/26456774
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