DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging

A major issue in aging research is how cellular phenomena affect aging at the systemic level. Emerging evidence suggests that DNA damage response (DDR) signaling is a key mechanism linking DNA damage accumulation, cell senescence, and organism aging. DDR activation in senescent cells promotes acquis...

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Foilsithe in:Oncotarget
Main Authors: Olivieri, Fabiola, Albertini, Maria Cristina, Orciani, Monia, Ceka, Artan, Cricca, Monica, Procopio, Antonio Domenico, Bonafè, Massimiliano
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2015
Ábhair:
Review: Gerotarget (Focus on Aging)
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742121/
https://ncbi.nlm.nih.gov/pubmed/26431329
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