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Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development

The concept of age-dependent host control of cancer development raises the natural question of how these effects manifest across the host tissue/organ types with which a tumor interacts, one important component of which is the aging immune system. To investigate this, changes in the spleen, an immun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Beheshti, Afshin, Wage, Justin, McDonald, J. Tyson, Lamont, Clare, Peluso, Michael, Hahnfeldt, Philip, Hlatky, Lynn
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742115/
https://ncbi.nlm.nih.gov/pubmed/26497558
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