Protease activated receptor-1 regulates macrophage-mediated cellular senescence: a risk for idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a destructive disease in part resulting from premature or mature cellular aging. Protease-activated receptor-1 (PAR-1) recently emerged as a critical component in the context of fibrotic lung diseases. Therefore, we aimed to study the role of macrophages in PAR...

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Publicat a:Oncotarget
Autors principals: Lin, Cong, Rezaee, Farhad, Waasdorp, Maaike, Shi, Kun, van der Poll, Tom, Borensztajn, Keren, Spek, C. Arnold
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper: Gerotarget (Focus on Aging)
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742106/
https://ncbi.nlm.nih.gov/pubmed/26474459
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