Chromosome transplantation as a novel approach for correcting complex genomic disorders

Genomic disorders resulting from large rearrangements of the genome remain an important unsolved issue in gene therapy. Chromosome transplantation, defined as the perfect replacement of an endogenous chromosome with a homologous one, has the potential of curing this kind of disorders. Here we report...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Paulis, Marianna, Castelli, Alessandra, Susani, Lucia, Lizier, Michela, Lagutina, Irina, Focarelli, Maria Luisa, Recordati, Camilla, Uva, Paolo, Faggioli, Francesca, Neri, Tui, Scanziani, Eugenio, Galli, Cesare, Lucchini, Franco, Villa, Anna, Vezzoni, Paolo
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Priority Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742100/
https://ncbi.nlm.nih.gov/pubmed/26485770
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