Epigenetic silencing of miR-145-5p contributes to brain metastasis

Brain metastasis is a major cause of morbidity and mortality of lung cancer patients. We assessed whether aberrant expression of specific microRNAs could contribute to brain metastasis. Comparison of primary lung tumors and their matched metastatic brain disseminations identified shared patterns of...

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Publicat a:Oncotarget
Autors principals: Donzelli, Sara, Mori, Federica, Bellissimo, Teresa, Sacconi, Andrea, Casini, Beatrice, Frixa, Tania, Roscilli, Giuseppe, Aurisicchio, Luigi, Facciolo, Francesco, Pompili, Alfredo, Carosi, Maria Antonia, Pescarmona, Edoardo, Segatto, Oreste, Pond, Greg, Muti, Paola, Telera, Stefano, Strano, Sabrina, Yarden, Yosef, Blandino, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Priority Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742098/
https://ncbi.nlm.nih.gov/pubmed/26440147
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