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Flagellin Encoded in Gene-Based Vector Vaccines Is a Route-Dependent Immune Adjuvant

Flagellin has been tested as a protein-based vaccine adjuvant, with the majority of studies focused on antibody responses. Here, we evaluated the adjuvant activity of flagellin for both cellular and humoral immune responses in BALB/c mice in the setting of gene-based immunization, and have made seve...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rady, Hamada F., Dai, Guixiang, Huang, Weitao, Shellito, Judd E., Ramsay, Alistair J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742079/
https://ncbi.nlm.nih.gov/pubmed/26844553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148701
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