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Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways

Angiogenesis and epidermal growth factor receptor (EGFR) inhibition has been shown to have anti-tumour efficacy, and enhance the therapeutic effects of cytotoxic chemotherapy in metastatic colorectal cancer. The interplay of signalling alterations and changes in metabolism and hypoxia in tumours fol...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Greening, David W., Lee, Sze Ting, Ji, Hong, Simpson, Richard J., Rigopoulos, Angela, Murone, Carmel, Fang, Catherine, Gong, Sylvia, O'Keefe, Graeme, Scott, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741991/
https://ncbi.nlm.nih.gov/pubmed/26517691
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