Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways

Angiogenesis and epidermal growth factor receptor (EGFR) inhibition has been shown to have anti-tumour efficacy, and enhance the therapeutic effects of cytotoxic chemotherapy in metastatic colorectal cancer. The interplay of signalling alterations and changes in metabolism and hypoxia in tumours fol...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Greening, David W., Lee, Sze Ting, Ji, Hong, Simpson, Richard J., Rigopoulos, Angela, Murone, Carmel, Fang, Catherine, Gong, Sylvia, O'Keefe, Graeme, Scott, Andrew M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741991/
https://ncbi.nlm.nih.gov/pubmed/26517691
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