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Epigenetic silencing of HIC1 promotes epithelial-mesenchymal transition and drives progression in esophageal squamous cell carcinoma

Downregulation of the novel tumor suppressor gene HIC1 (hypermethylated in cancer 1) occurs frequently in various tumors where it causes tumor progression and metastasis. In this study, we investigated a role of HIC1 in esophageal squamous cell carcinoma (ESCC) and the underlying mechanisms. Downreg...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Pei, Liu, Xiang, Dong, Zi-Ming, Ling, Zhi-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741990/
https://ncbi.nlm.nih.gov/pubmed/26510908
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