Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells

Distant relapse after chemotherapy is an important clinical issue for treating breast cancer patients and results from the development of cancer stem-like cells (CSCs) during chemotherapy. Here we report that blocking epithelial-to-mesenchymal transition (EMT) suppresses paclitaxel-induced CSCs prop...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Park, So-Yeon, Kim, Min-Jin, Park, Sang-A, Kim, Jung-Shin, Min, Kyung-Nan, Kim, Dae-Kee, Lim, Woosung, Nam, Jeong-Seok, Sheen, Yhun Yhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741946/
https://ncbi.nlm.nih.gov/pubmed/26462028
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