Targeting stemness is an effective strategy to control EML4-ALK(+) non-small cell lung cancer cells

The fusion between anaplastic lymphoma kinase (ALK) and echinoderm microtubule-associated protein-like 4 (EML4) is a causative factor in a unique subset of patients with non-small cell lung carcinoma (NSCLC). Although the inhibitor crizotinib, as it blocks the kinase activity of the resulting EML4-A...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Oh, Se Jin, Noh, Kyung Hee, Lee, Young-Ho, Hong, Soon-Oh, Song, Kwon-Ho, Lee, Hyo-Jung, Kim, Soyeon, Kim, Tae Min, Jeon, Ju-Hong, Seo, Jae Hong, Kim, Dong-Wan, Kim, Tae Woo
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741893/
https://ncbi.nlm.nih.gov/pubmed/26517679
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