PIK3CA mutation detection in metastatic biliary cancer using cell-free DNA

PIK3CA mutation is considered a good candidate for targeted therapies in cancers, especially biliary tract cancer (BTC). We evaluated the utility of cell free DNA (cfDNA) from serum by using droplet digital PCR (ddPCR) as an alternative source for PIK3CA mutation analysis. To identify matching archi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Seung Tae, Lira, Maruja, Deng, Shibing, Lee, Sujin, Park, Young Suk, Lim, Ho Yeong, Kang, Won Ki, Mao, Mao, Heo, Jin Seok, Kwon, Wooil, Jang, Kee-Taek, Lee, Jeeyun, Park, Joon Oh
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741877/
https://ncbi.nlm.nih.gov/pubmed/26498688
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