Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts

Ultraviolet radiation B (UVB) is the main cause of DNA damage in epidermal cells; and if not repaired, this DNA damage leads to skin cancer. In earlier studies, we have reported that natural flavonolignan silibinin exerts strong chemopreventive efficacy against UVB-induced skin damage and carcinogen...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Guillermo-Lagae, Ruth, Deep, Gagan, Ting, Harold, Agarwal, Chapla, Agarwal, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741848/
https://ncbi.nlm.nih.gov/pubmed/26447614
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