Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer's disease: identification of common and distinct olfactory targets across Alzheimer-related co-pathologies

Olfactory dysfunction is present in up to 90% of Alzheimer's disease (AD) patients. Although deposition of hyperphosphorylated tau and β-amyloid substrates are present in olfactory areas, the molecular mechanisms associated with decreased smell function are not completely understood. We have ap...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Zelaya, María Victoria, Pérez-Valderrama, Estela, de Morentin, Xabier Martínez, Tuñon, Teresa, Ferrer, Isidro, Luquin, María Rosario, Fernandez-Irigoyen, Joaquín, Santamaría, Enrique
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
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Research Paper: Gerotarget (Focus on Aging)
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741837/
https://ncbi.nlm.nih.gov/pubmed/26517091
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