MUC4-promoted neural invasion is mediated by the axon guidance factor netrin-1 in PDAC

Neuralinvasion (NI) is an important oncological feature of pancreatic ductal adenocarcinoma (PDAC). However, the underlying mechanism of NI in PDAC remains unclear. In this study, we found that MUC4 was overexpressed in PDAC tissues and high expression of MUC4 indicated a higher NI incidencethan low...

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Udgivet i:Oncotarget
Main Authors: Wang, Linjun, Zhi, Xiaofei, Zhu, Yi, Zhang, Qun, Wang, Weizhi, Li, Zheng, Tang, Jie, Wang, Jiwei, Wei, Song, Li, Bowen, Zhou, Jianping, Jiang, Jianguo, Yang, Li, Xu, Hao, Xu, Zekuan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741804/
https://ncbi.nlm.nih.gov/pubmed/26393880
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