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t-Darpp overexpression in HER2-positive breast cancer confers a survival advantage in lapatinib

Drug resistance is a major barrier to successful cancer treatment. For patients with HER2-positive breast cancer who initially respond to therapy, the majority develop resistance within one year of treatment. Patient outcomes could improve significantly if we can find and exploit common mechanisms o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Christenson, Jessica L., Denny, Erin C., Kane, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741754/
https://ncbi.nlm.nih.gov/pubmed/26430732
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