MiR-208a stimulates the cocktail of SOX2 and β-catenin to inhibit the let-7 induction of self-renewal repression of breast cancer stem cells and formed miR208a/let-7 feedback loop via LIN28 and DICER1

MiR-208a stimulates cardiomyocyte hypertrophy, fibrosis and β-MHC (β-myosin heavy chain) expression, being involved in cardiovascular diseases. Although miR-208a is known to play a role in cardiovascular diseases, its role in cancer and cancer stem cells (CSCs) remains uncertain. We identified an in...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sun, Xin, Jiang, Shiwen, Liu, Jian, Wang, Huangzhen, Zhang, Yiwen, Tang, Shou-Ching, Wang, Jichang, Du, Ning, Xu, Chongwen, Wang, Chenguang, Qin, Sida, Zhang, Jia, Liu, Dapeng, Zhang, Yunfeng, Li, Xiaojun, Wang, Jiansheng, Dong, Jun, Wang, Xin, Xu, Shaohua, Tao, Zhen, Xu, Fei, Zhou, Jie, Wang, Tao, Ren, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741741/
https://ncbi.nlm.nih.gov/pubmed/26460550
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