The search for cis-regulatory driver mutations in cancer genomes

With the advent of high-throughput and relatively inexpensive whole-genome sequencing technology, the focus of cancer research has begun to shift toward analyses of somatic mutations in non-coding cis-regulatory elements of the cancer genome. Cis-regulatory elements play an important role in gene re...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Poulos, Rebecca C., Sloane, Mathew A., Hesson, Luke B., Wong, Jason W. H.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741709/
https://ncbi.nlm.nih.gov/pubmed/26356674
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