c-Met inhibitors attenuate tumor growth of small cell hypercalcemic ovarian carcinoma (SCCOHT) populations

A cellular model (SCCOHT-1) of the aggressive small cell hypercalcemic ovarian carcinoma demonstrated constitutive chemokine and growth factor production including HGF. A simultaneous presence of c-Met in 41% SCCOHT-1 cells suggested an autocrine growth mechanism. Expression of c-Met was also observ...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Otte, Anna, Rauprich, Finn, von der Ohe, Juliane, Yang, Yuanyuan, Kommoss, Friedrich, Feuerhake, Friedrich, Hillemanns, Peter, Hass, Ralf
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741630/
https://ncbi.nlm.nih.gov/pubmed/26436697
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