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Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas

The c-Myc gene codes for a basic-helix-loop-helix-leucine zipper transcription factor protein and is reported to be frequently over-expressed in human cancers. Given that c-Myc plays an essential role in neoplastic transformation we wished to define its activity in lung cancer and therefore studied...

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Publicat a:Oncotarget
Autors principals: Ciribilli, Yari, Singh, Prashant, Spanel, Reinhard, Inga, Alberto, Borlak, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741625/
https://ncbi.nlm.nih.gov/pubmed/26427040
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